Denosyl Tablets. Aids in liver detoxification mechanisms.

S-Adenosylmethionine increases hepatic glutathione levels in cats and dogs. Glutathione is a potent antioxidant that protects the liver from toxins and death. Low liver glutathione concentrations are common in dogs and cats with decreased liver function.

Administration of S-Adenosylmethionine may improve glutathione levels in liver cells to help maintain and protect liver function.

S-Adenosylmethionine may also be used in other areas of tissue oxidant injury and red blood cell fragility caused by certain toxins or drugs which are related to reduced glutathione concentrations. S-Adenosylmethionine also protects liver cells from cell death and may be useful in cell regeneration. S-Adenosylmethionine may also improve bile flow in cats.

Dosage and Administration:
Daily administration is based on 20 mg of S-adenosylmethionine/kg bodyweight. Because the (enteric coated) tablet must be kept intact to prevent destruction by stomach acid, administration range is based on the nearest whole tablet.

Tablets (90 mg) for cats and small dogs.
Up to 5.9 kg bodyweight: 1 tablet. 

Tablets (225 mg) for medium dogs.
6 to 15.9 kg: 1 tablet
16 to 29.9 kg: 2 tablets (or 1 large (425 mg) tablet). 

Tablets (425 mg) for large dogs.
16 to 29.9 kg: 1 tablet (or 2 medium (225 mg) tablets).
30 to 54.9 kg: 2 tablets.
Over 55 kg: 3 tablets.

For optimal absorption, give tablets on an empty stomach, at least one hour before feeding. Administer a few millilitres of water immediately following any tablet administration to speed passage of the tablet into the stomach. For those owners who have difficulty administering tablets to their pets, Denosyl Tablets may be disguised in a small bite of food.